Archived: 8th Winter Conference
on Medicinal & Bioorganic Chemistry
January 21st - 25th 2007
Steamboat Springs Resort, Colorado
Agenda
Sunday, January 21st 2007
Orphan Drugs
Program Chair: Lester A. Mitscher, University of Kansas
Orphan Drugs: An Ever Expanding Drug Category
Development of New Therapies against Tuberculosis
Antimalarial Chemotherapy in the 21st Century; Recent Advances in the Development of Drugs Targeting the Hemoglobin Degradation Pathway
Monday, January 22nd 2007
General Oral Session
Program Chair: Bryan Norman, Eli Lilly & Company
Methods for Fluoro Substituent Introduction into Organic Molecules
Program Chair: Victor Snieckus, Queen’s University
A New View of the Role of Fluorine in Medicinal Chemistry
Recent Progress with Nucleophilic Fluorinating Agents
Construction of Fluorinated Heterocycles by Using the Characteristic Reactivities of Fluoro Alkenes
Tuesday, January 23rd 2007
Update on the Discovery of Liver-X-Receptor (LXR) Agonists to Raise HDL
Program Chair: Jeff Zablocki, CVTherapeutics
Mixed and alpha-Selective LXR Agonists and their Effects in vivo
A Novel Series of Tetracyclic Acridines as Potent LXR Activators
A Lesson from the LXR Alphabet…It’s Not Just About the ABCs
Design of Potent and Selective LXR Agonists from a Series of Quinoline and Indazole Core Compounds
Biomedical Imaging and Diagnostics
Program Chair: Tony Barrett, Imperial College
England Analysis, Microscopy and Imaging with Lanthanide Probes
Developing Fluorescent Probes for Biomedical Imaging
Fluorescent Dyes under Influence: Design of Cyanine Conjugates for Optical Molecular Imaging
High Relaxivity and High Stability in Gd MRI Agents
Wednesday, January 24th 2007
Recent Advances in Organic Chemistry
Program Chair: Robert M. Williams, Colorado State University
From Microcycles to Macrocycles: Azapenams to Dioxocyclams
Methods for and Applications of Helical Peptide Self-Assembly
Catalytic Asymmetric C-C and C-N Bond-Forming Reactions
Oxidation of Olefins
Discovery by Synethesis: New Methods for Deoxygenation
Chiral Oxazolines – Their Legacy in Asymmetric C-C Bond Forming Reactions
Poster Session
Program Chair: Jack Hodges, Berry & Associates
Sunshine Peak/Mt. Werner
Thursday, January 25th 2007
Picking the Right Pocket: Advances in non-ATP Kinase Inhibitor Design
Program Chair: Michael Rafferty, Deciphera Pharmaceuticals
Non-ATP Competitive Inhibitors of Serine/Theronine and Tyrosine Kinases for Cancer Therapy
Mimicry of Endogenous Kinase Regulation. Small Molecule Modulators of Kinase Conformational Switching Pockets
Preclinical Development of RAF265: A Novel and Potent Inhibitor of Mutant B-Raf
Fragmented-based Discovery of BCR-ABL Inhibitors for Treatment of Chronic Myelogenous Leukaemia
Synthesis and Discovery of a Novel Multi-targeted Anti-angiogenic Kinase Inhibitor (MAK)
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