Archived: 2nd Winter Conference
on Medicinal & Bioorganic Chemistry
January 26th - 31st 1997
Steamboat Springs Resort, Colorado
Agenda
Sunday, January 26th 1997
Asymmetric Catalysis inorganic Synthesis
Program Chair: Victor Snieckus, University of Waterloo
Overview: Catalysis in Asymmetric Synthesis
Development and Use of Transition Metal Catalysis and Reagents in Organic Synthesis
Monday, January 27th 1997
Asymmetric Catalysis in Organic Synthesis (cont.)
Program Chair: Victor Snieckus, University of Waterloo
Chiral Oxazolines as Ligands in Asymmetric Catalysts
Selective Enzymatic and Electrochemical Methods of Oxidation and Reduction. Specificity and Synthetic Utility.
Synthesis and Design of Synthesis Enzymes: Mn(II) Pentaaza Macrocyclic Ligand Complexes as Superoxide Dismutase Mimics and their Utility as Therapeutics
Controlling Chemical Reactivity Using Unnatural Catalysts
Synthesis on Solid Support
Program Chair: Anthony G.M. Barrett, Imperial College
Solid-Phase Organic Synthesis: and Introduction and Overview
Reaction and Structure Templated in Sloid Support Synthesis
Development of Synthesis Methods Suitable for Applications in Combinatorial Chemistry
Tuesday, January 28th 1997
Synthesis on Solid Support (cont.)
Program Chair: Anthony G.M. Barrett, Imperial College
Constructing Organic Compounds on Solid Phase
New Solid-Supported Reagents and their Utilities
New Methods in Solid Phase Synthesis
Combinatorial Chemistry: Update and Appraisal
Program Chair: Eric M. Gordon, Versicor
Introduction to Combinatorial Chemistry
Interfacing Structure-Based Design and Combinatorial Chemistry
Pathways for the Development of Combinatorial Technologies
Strategies for Lead Discove5ry: Synthesis and Evaluation of N-coded Synthetic Combinatorial Libraries
Resin Chemistries and Bead Technologied for Use in Combinatorial Chemistry and Lead Discovery
Wednesday, January 29th 1997
KEYNOTE | “Exploring Biological Catalysis”
Program Chair: Stephen Benkovic, Penn State University
General Oral Papers
Thursday, January 30th 1997
Molecular Recognition in Drug Design
Program Chair: Patrick Y. Lam, DuPont Merck
Molecular Recognition in Drug Design: Overview and Selected Examples
Molecular Recognition in Organic and Biological Chemistry
Caption-pi Interactions in Chemistry and Molecular Neurobiology
New Twists in the Killing of Super Bugs
Peptide Related Research: A Means to Chemical and Biological Understanding
Src SH2 Structure-based Drug Design
Caption-pi Interactions in Structure-based Design of Potent and Selective Inhibitors of Matrix Metalloproteinases
Friday, January 31st 1997
Drug Delivery: Problems and Strategies
Program Chair: Valentino Stella, University of Kansas / Michael D. Taylor, Parke-Davis
- Overview: Barriers to Efficient Drug Delivery
- Delivery of Sparingly Soluble Drugs
Membrane Transport as a Barrier to Drug Delivery
Predicting Human Bioavailability and Pharmacokinetics from Preclinical Data
Overview: Delivery Strategies and Drug Design
Formulation, Prodrug and Analog Approaches to Improving Oral Bioavailability
Prodrug Strategies for Enhanced and Targeted Delivery of Therapeutic Agents
Recent Advances in Transdermal (and/or Oral Controlled Releases) Technologies
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