17th Winter Conference
on Medicinal & Bioorganic Chemistry

February 2 - 6, 2025

Steamboat Grand Resort, Colorado

Agenda

Sunday, February 2nd 2025

Drug Hunter Award Session

Program Chair: Jennifer Venable

Brian Lanman Amgen

Drug Hunter Award:

Evolving Strategies in Targeting KRAS

Renata Oballa Chinook Therapeutics

Discovery of CHK-336: A Liver-Targeted, Small Molecule Lactate Dehydrogenase Inhibitor for Hyperoxaluria Treatment

Fred Cohen Nurix

Title to be confirmed

Nuria Diaz Eli Lilly

Discovery of Muvalaplin: the first oral molecule inhibitor of Lp(a) formation in Clinical Trials

Networking Session

Welcome Reception

Monday, February 3rd 2025

Modern Synthetic Toolbox and Technologies for Drug Discovery and Development

Program Chair: Ying Wang

Mark Levin University of Chicago

Inserting, Deleting, and Replacing Atoms

Eric Voight AbbVie

Title to be Confirmed

Lisa Marcaurelle GSK

Title to be Confirmed

Kian Tan Novartis

Living in Uncertainty: Application of Active Learning in Drug Discovery

Christina White University of Illinois

Title to be Confirmed

Leveraging Chemically Induced Proximity in Drug Discovery

Program Chair: Kevin Freeman-Cook

Ryan Potts Amgen

Redefining Druggability with Induced Proximity Modalities

Kat Kayser-Bricker Halda

Hold and Kill: RIPTAC™ Therapeutics Present a Novel Induced-Proximity Mechanism to Conquer Cancer

Yongxin Han Nested

Title to be Confirmed

Jackson Gartman AbbVie

The Hunt for Ligands for Tissue-Restricted Ligases

Jacob Edwards BMS

Title to be confirmed

Tuesday, February 4th 2025

Therapeutic Opportunities for Immune Modulators

Program Chair: Hanna Wisniewska

Stephen Murphy Johnson & Johnson Innovative Medicine

Development of Non-alkynyl NIK Inhibitors

Steve Canham Novartis

Discovery of C-terminal and N-terminal binding STING agonists

Scott D. Edmondson Nimbus Therapeutics

Switching the Immune System Off and On Through Computationally Enabled Drug Discovery: The Discovery of TYK2 Inhibitor TAK-279 for Immune Disorders and HPK1 Inhibitor NDI-101150 for Cancer

Daniel Smaltz Pfizer

Title to be confirmed

General Session - Synthesis and Medicinal Chemistry

Program Chair: Aaron Roth

Submit an Abstract for Consideration E-mail: claire@scientificupdate.com

Networking Session

POSTER SESSION

Wednesday. February 5th 2025

Advances in Bioconjugate Chemistry

Program Chair: Natalia Chernyak

Monika Raj Emory University

Chemical Probes for Biological Discoveries

Shalom Goldberg Johnson & Johnson

Title to be confirmed

Nathan Tumey Binghamton University

Title to be Confirmed

Marion Emmert Merck

Title to be confirmed

Andy Judd AbbVie

Title to be confirmed

Robert M. Williams' Memorial KEYNOTE LECTURE

Program Chair: Nootaree Niljianskul

Sherry Niessen BelharraTx

Developing a Novel and High-Throughput Chemoproteomic Platform to Identify Druggable Pockets and Chemical Probes for Disease Relevant Proteins

Jon Mortison Merck

Approaches to Targeting RNA with Small Molecules

Denise Field Pfizer

Large-Scale Chemoproteomics Expedites Drug Discovery and Predicts Ligand Behavior in Cells

Kevan Shokat UCSF

KEYNOTE:  Overcoming the Undruggable Nature of the Most Common Human Oncogene K-Ras

Networking Session

Robert M. Williams' Memorial RECEPTION

Thursday, February 6th 2025

Late Breaking / First Time Disclosures

Program Chair: Joe Pero

Hanna Wisniewska Pfizer

Title to be confirmed

Chris amEnde Pfizer

Title to be confirmed

Noel Wilson AbbVie

Title to be confirmed

Networking Session

Conference Dinner - Top of the Gondola

Become a Sponsor

Sponsor any of our activities and solicit your suggestions on how we can continue to serve the medicinal and bioorganic chemistry research community.

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Submitting an article

There are two opportunities for you to present your work at this conference

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Enquiries

For papers, sponsorship information and abstract submissions for our next conference in 2025 please contact our Conference Manager – Dr Claire Francis

Media Sponsors

Bronze sponsors