Archived: 4th Winter Conference
on Medicinal & Bioorganic Chemistry
January 28th - February 2nd 2001
Steamboat Springs Resort, Colorado
Agenda
Sunday, January 28th 2001
Modern Heterocyclic Construction
Program Chair: Victor Snieckus, Queen’s University
Catalytic Enantioselective and Practical Olefin Metathesis Reactions
New Synthetic Methods for Bioactive Heterocycles
New Organometalice Mediated Cross-Coupling Reactions for the Construction of Complex Biologically Important Natural Products
Monday, January 29th 2001
Modern Heterocyclic Construction (cont.)
Program Chair: Victor Snieckus, Queen’s University
Catalytic Cascade Reactions: Routes to Potentially Bio-Active Complex Heterocycles
New Wrinkles on Old Reactions in Heterocyclic Chemistry: Applications to Alkaloid Total Synthesis
Constructing Substituted Heterocycles: Comparing Directed ortho Metalation with Other Selected Methodologies
Cascade Processes for Heterocyclic Synthesis
Target-Driven Approaches to Anticancer Agents
Program Chair: Bryan H. Norman, Eli Lilly and Co
Evolving Molecular Targets for Anticancer Drug Discovery
Inhibition of Cyclin Dependent Kinases as an Approach to Cancer Therapy
The Discovery & Preclinical Development of Benzodiazepine Farnsey Intransferase Inhibitors
Tyrosine Kinase Inhibitors from Rational Design to Clinical Trials
Tuesday, January 30th 2001
Pharmacokinetics for Medicinal Chemists
Program Chair: David Lau, Amgen Inc.
Building Blocks on Basic Pharmacokinetics Concepts for Medicinal Chemists in Drug Discovery Support
Metabolism Issues for Small Molecule Drug Discovery and Development
Recent Advances in the Structural Biology of Seven Transmembrane Receptors
Program Chair: Daniel Flynn, Millennium Pharmaceuticals
State of the 7TMG- Protein Union – Lessons from Metal-ion Site Engineering and Fusion Proteins
Peptide Hormone Binding to GPCR Receptors: Structural Characterization via NMR Techniques
Modelling the 3D Structure of G-Protein Couples Receptors from Primary Sequence
Wednesday, January 31st 2001
General Papers
Program Chair: Mike VanNieuwenhze
KEYNOTE | Vancomycin, Teicoplanin and Ramoplanin: Synthetic & Mechanistic Studies
Program Chair: Dale Boger, Scripps Research Institute
Thursday, February 1st 2001
Nuclear Hormone Receptors
Program Chair: Lawrence G. Hamann, Bristol-Myers Squibb
New PPAR Modulators: Diabetes and Beyond
Rexinoid Receptor Signalling Pathways as Targets for Drug Development
Metabolic Regulation through Orphan Nuclear Receptors
Ligand Specificity in RXP, RAR and VDR
Novel Ligands for Estrogen Receptor Alpha and Beta
Nuclear Receptor-Cofactor Interactions as Targets for New Drug Discovery
Friday, February 2nd 2001
Alkene Metathesis
Program Chair: Anthony G.M. Barrett, Imperial College
Sequential Olefin Metathesis – Applications in Natural Product Synthesis
Alkene Metathesis Applications from Small Molecules to ROMPGELs
The Use of Ruthenium Carbenes in Synthesis
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